2019
Jasmine Theis, Tilak Kumar Gupta, Johannes Klingler, William Wan, Sahradha Albert, Sandro Keller, Benjamin D Engel, Michael Schroda. VIPP1 rods engulf membranes containing phosphatidylinositol phosphates. Sci. Rep. (2019) 9; 8725.
doi: 10.1038/s41598-019-44259-3
Anna Rast, Miroslava Schaffer, Sahradha Albert, William Wan, Stefan Pfeffer, Florian Beck, Jürgen M. Plitzko, Jörg Nickelsen & Benjamin D. Engel. Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane. Nature Plants. (2019) 5; 436 – 446
doi: 10.1038/s41477-019-0399-7
2017
William Wan, Larissa Kolesnikova, Mairi Clarke, Alexander Koehler, Takeshi Noda, Stephan Becker, John A.G. Briggs. Structure and assembly of the Ebola virus nucleocapsid. Nature. (2017) 551; 394 – 397
doi: 10.1038/nature24490
Beata Turoňová, Florian K.M. Schur, William Wan, John A.G. Briggs. Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4 Å. J. Struct. Biol. (2017) 199; 187 – 195
doi: 10.1016/j.jsb.2017.07.007
Wim J. H. Hagen, William Wan, John A. G. Briggs. Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging. J. Struct. Biol. (2017) 197; 191 – 198
doi: 10.1016/j.jsb.2016.06.007
2016
William Wan, John A. G. Briggs. Cryo-electron tomography and subtomogram averaging. Methods Enzymol. (2016) 579; 329 – 367
doi: 10.1016/bs.mie.2016.04.014
Florian K.M. Schur, Martin Obr, Wim J.H. Hagen, William Wan, Arjen J. Jakobi, Joanna M. Kirkpatrick, Carsten Sachse, Hans-Georg Kräusslich, John A.G. Briggs. An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation. Science (2016) 353; 506 – 508
doi: 10.1126/science.aaf9620
Jan Kosinski, Shyamal Mosalaganti, Alexander von Appen, Roman Teimer, Amanda L. DiGuilio, William Wan, Khanh Huy Bui, Wim J.H. Hagen, John A.G. Briggs, Joseph S. Glavy, Ed Hurt, Martin Beck. Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science (2016) 352; 363 – 365
doi: 10.1126/science.aaf0643
Marcus D Tuttle, Gemma Comellas, Andrew J Nieuwkoop, Dustin J Covell, Deborah A Berthold, Kathryn D Kloepper, Joseph M Courtney, Jae K Kim, Alexander M Barclay, Amy Kendall, William Wan, Gerald Stubbs, Charles D Schwieters, Virginia MY Lee, Julia M George, Chad M Rienstra. Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat. Struct. Mol. Biol. (2016) 23; 409 – 415
doi: 10.1038/nsmb.3194
William Wan, Jan Stöhr, Amy Kendall, Gerald Stubbs. Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure. Prion (2016) 9; 333 – 338
doi: 10.1080/19336896.2015.1084464
2015
Maruda Shanmugasundaram, Dmitry Kurouski, William Wan, Gerald Stubbs, Rina K. Dukor, Laurence A. Nafie, Igor K. Lednev. Rapid Filament Supramolecular Chirality Reversal of HET-s (218–289) Prion Fibrils Driven by pH Elevation. J. Phys. Chem. B (2015) 119; 8521 – 8525
doi: 10.1021/acs.jpcb.5b04779
William Wan*, Holger Wille*, Jan Stöhr, Amy Kendall, Wen Bian, Michele McDonald, Sarah Tiggelaar, Joel C. Watts, Stanley B. Prusiner, Gerald Stubbs. Structural studies of truncated forms of the prion protein PrP. Biophys. J. (2015) 108; 1548 – 1554
doi: 10.1016/j.bpj.2015.01.008
2014
William Wan, Gerald Stubbs. Fiber diffraction of the prion-forming domain HET-s(218–289) shows dehydration-induced deformation of a complex amyloid structure. Biochemistry. (2014) 53; 2366 – 2370
doi: 10.1021/bi5002807
William Wan, Gerald Stubbs. The fungal prion HET-s as a model for structural complexity and self-propagation in prions. Proc. Natl. Acad. Sci. U.S.A. (2014) 111; 5201 – 5206
doi: 10.1073/pnas.1322933111
William Wan, Gerald Stubbs. Heterogeneous seeding of HET-s(218-289) and the mutability of prion structures. Prion. (2014) 8; 178 – 182
doi: 10.4161/pri.28126
Dmitry Kurouski, Xuefang Lu, Ludmila A. Popova, William Wan, Maruda Shanmugasundaram, Gerald Stubbs, Rina K. Dukor, Igor K. Lednev, and Laurence A Nafie. Is supramolecular proto- filament chirality the underlying cause of major morphology differences in amyloid fibrils? J. Am. Chem. Soc. (2014) 136; 2302 – 2312
doi: 10.1021/ja407583r
2013
William Wan, Wen Bian, Michele McDonald, Aleksandra Kijac, David E. Wemmer, Gerald Stubbs. Heterogeneous seeding of a prion structure by a generic amyloid form of the fungal prion-forming domain HET-s(218-289). J. Biol. Chem. (2013) 288; 29604 – 29612.
doi: 10.1074/jbc.M113.505511
2012
William Wan, Holger Wille, Jan Stöhr, Ulrich Baxa, Stanley B. Prusiner, Gerald Stubbs. Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold. Biophys. J. (2012) 102; 2339 – 2344.
doi: 10.1016/j.bpj.2012.04.011
2009
Ming Li, William N. Wan, Olga Petrova, Feilei Huang, Zhenzhen Zhou, Patrick Boyd, Karl A. Wilson and Anna Tan-Wilson. Applicability of multigene family-specific antibodies toward studies of the subtilases in Arabidopsis thaliana. Anal. Biochem. (2009) 384; 114 – 122.
doi: 10.1016/j.ab.2008.09.024